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Does the endocannabinoid system have an effect on exercise euphoria?

What causes a runner’s high? Is it CBD, endorphins or our endocannabinoid systems?

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Home » News » Does the endocannabinoid system have an effect on exercise euphoria?

The euphoric feeling after exercise, often referred to as a ‘runner’s high’, is associated with a reduction in pain, stress and anxiety.

Research now links the runner’s high to our endocannabinoid system, suggesting that the exercise-induced endorphin release it was always attributed to, is not solely responsible.

But what is our endocannabinoid system? And how does it work? 

We examine endocannabinoids, endorphins and how CBD plays a part in balancing the body and exercise

What is the endocannabinoid system?

The endocannabinoid system is thought to regulate different functions in the body such as sleep, mood, appetite, memory and fertility. It is made up of receptors, enzymes and endocannabinoids.

Endocannabinoid receptors are found naturally all over the body. There are two major receptors called CB1 and CB2.

CB1 is usually found in the central nervous system, while CB2 is found in the peripheral nervous system. Endocannabinoids bind to the receptors to help with different problems such as pain. It is not fully understood how cannabinoids bind with receptors.

Endocannabinoids are actually naturally produced molecules that are similar to cannabinoids. So far, researchers have identified two key endocannabinoids: anandamide (AEA) and 2-arachidonoylglyerol (2-AG).

Enzymes break down the endocannabinoids once they are no longer needed. The two major enzymes are fatty acid amide hydrolase, which breaks down AEA and monoacylglycerol acid lipase, which typically breaks down 2-AG.

What is the difference between endocannabinoids and endorphins?

Endorphins are chemicals released by the body in response to pain or exercise. They were traditionally associated with the euphoria felt after a run. However, endorphins cannot cross into the brain through the blood-brain barrier which exists to protect the brain from toxins and pathogens. 

This is one of the reasons that scientists suspect it may not be the reason for the high. They may keep you from experiencing pain after a run.

How does CBD feature in all of this?

CBD interferes with the receptors found in the endocannabinoid system to help them balance the body. However, it is not fully understood how this happens.

CBD, unlike tetrahydrocannabinol (THC), another cannabinoid found in the plant, does not bind the receptors. CBD may supplement the endocannabinoid system helping to regulate your system. The cannabinoids travel the receptor that has been stimulated and needs extra help to achieve a balance.  Depending on the dose and which receptor it is, CBD is thought to help anxiety, sleep problems, inflammation and pain.

This is why a lot of runners or athletes depend on CBD as part of their recovery routine after a strenuous workout. It may help to alleviate some of the muscle pain they endure during a run.

 

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