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How CBD is helping women with endometriosis

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Women around the world are increasingly using CBD to deal with the symptoms of endometriosis – a much misunderstood and misdiagnosed condition. Cannabis Health finds out more.

Endometriosis is the second most common gynecological condition in the UK, affecting around one in 10 UK women – although frequent misdiagnosis and a lack of understanding means this figure may be higher.

It happens when tissue similar to the lining of the womb starts to grow in other places, such as the ovaries and fallopian tubes, which then reacts to the menstrual cycle each month and also bleeds.

However, there is no way for this blood to leave the body, causing inflammation, pain and the formation of scar tissue.

Nobody knows what causes it, or why some women suffer and others don’t, and symptoms, including pain in the lower abdomen and back, nausea, intense fatigue and infertility, can be debilitating.

According to Endometriosis UK, it takes an average of seven and a half years from onset of symptoms to get a diagnosis, and the condition costs the UK economy £8.2bn a year in treatment, loss of work and healthcare costs.

There is currently no cure, and treatment is limited to painkillers, hormonal contraception, or surgery to cut away the scar tissue. In more severe cases, the only option may be a full hysterectomy to remove part or all of the affected organs.

But could there be another way? More and more women are turning to CBD to ease their symptoms, and the results are encouraging.

Charlotte Nichols, managing director of North East of England-based PR firm Harvey & Hugo, has been using a CBD oil for a couple of months, and has already noticed a difference in her symptoms.

She explained: “I was diagnosed with endometriosis in 2017 but I’d been suffering with it for three years before that; it took that long to diagnose as it was just put down to ‘just’ painful periods.

“I had surgery to remove it but still struggled with infertility, until I finally got pregnant in 2018. The symptoms disappeared while I pregnant and breastfeeding but then came back with a bang since – I’d forgotten how awful it was.”

After researching how CBD could help, Charlotte began taking the oil in June 2020, and the results have been significant.

She said: “While the CBD doesn’t stop the pain completely, it definitely helps take the edge of the symptoms.

“Stress and lack of sleep both make my symptoms worse, and the oil has definitely helped with this, helping me relax and dramatically improving my sleep.

“I’ve also found that the CBD has improved my mood, as feeling so rubbish all the time was getting me down. That might be the effect of the oil itself, or simply because it’s alleviating the symptoms    – either way, it’s making me feel more like myself again.”

While using CBD as a painkiller is nothing new, experts believe that its use for endometriosis may be down to more than simple pain relief.

Research has found that cannabinoids also help by:

  • Stopping the endometrial cells from multiplying
  • Preventing them from migrating to other parts of the reproductive system
  • Stopping the blood supply to the lesions – effectively starving them of the nutrients they need to grow
  • Regulating nerve growth
  • Reducing inflammation
  • Modulating the immune response
  • Desensitising the nerves that transmit pain.

In fact, some scientists believe that dysfunction in a woman’s endocannabinoid system – the molecular system responsible for regulating and balancing processes in the body, including immune response – may be behind endometriosis.

Dr Michele Ross, CEO of Infused Health, explains: “Reduced function of the endocannabinoid system leads to the growth of endometriosis throughout the body, and more pain.”

CB1 cannabinoid receptors mediate the pain from endometriosis and, according to a 2010 study, are present in the cells that supply nerve impulses to the endometrial growth.

However, the endometrial cells of women with endometriosis have been found to have a lower expression of CB1 receptors — so activating the few that are expressed is even more important for those in pain.

Whatever the science behind it, women like Charlotte are just pleased to finally have a natural product to alleviate their symptoms.

“I much prefer taking CBD to other painkillers, as I’m very aware of what I’m putting into my body and, as far as I’m concerned, the more natural the better,” she says.

“At the moment I’m just using the oil; I haven’t tried any other products, like the balms or lotions, but I’m going to look into it.

“I also find that exercise, intermittent fasting, avoiding alcohol and cutting down on sugar really helps my symptoms, in combination with the CBD. It’s been a long road, with a lot of trial and error along the way, but I’m so glad to finally feel in control of my body again.”

Advocacy

Fair Trials and Last Prisoner Project seek to launch global cannabis justice project

Fair Trials’ Global CEO Norman L. Reimer to discuss the project at Cannabis Europa Conference in London on June 29.

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A new initiative from Fair Trials and the Last Prisoner Project aims to redress the harm caused by cannabis prohibition and to secure relief for those in prison for cannabis-related convictions.

The criminal justice reform NGO, Fair Trials hopes that the industry will support its work in countries across the globe where cannabis laws are being liberalised. Through collaboration with local partners in appropriate jurisdictions, the Fair Trials project will identify people in need of legal assistance, and recruit, train and match volunteer lawyers to take on their cases.

Fair Trials has enlisted the help of the Last Prisoner Project, a coalition of cannabis industry leaders, executives and artists dedicated to bringing restorative justice to the cannabis sector.

More and more jurisdictions are allowing adults to use and distribute medical and recreational cannabis. But after decades of prohibition, countless people remain behind bars or continue to suffer the collateral consequences of a cannabis conviction.

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“The injustice of cannabis prohibition has resulted in millions of people worldwide serving time in prison or being saddled with a cannabis conviction, which brings with it a lifetime of harmful consequences, ranging from education and employment opportunities to immigration status and parental rights,” said Fair Trials Global CEO, Norman L Reimer.

“Of course, these harmful effects of prohibition not only impact the individuals charged, but also their families and communities. And those effects have been borne disproportionately by minorities, communities of colour, and the socio-economically disadvantaged. Legalising cannabis alone does not equal justice. Together, we must address the ongoing harms of past prohibition and leave no cannabis prisoner behind.”

The project will be modelled on the US Cannabis Justice Initiative, a collaborative effort between the cannabis industry and volunteer lawyers in the United States. When Norman Reimer was the Executive Director of the National Association of Criminal Defense Lawyers (NACDL), he partnered with the Last Prisoner Project to establish the initiative.

“Key to the success of the initiative has been generous donations from legal cannabis companies and consumers nationwide,” said Last Prisoner Project Co-Founder Steve DeAngelo. “Fair Trials, with its global reach as the world’s criminal justice watchdog, is uniquely positioned to build and house the infrastructure that’s going to be needed.”

Tomorrow (29 June), Norman Reimer will address the Cannabis Europa Conference discussing the project. Mr Reimer will be part of a panel entitled ‘Leave No Cannabis Prisoner Behind,’ and will be joined on that panel by Mary Bailey, Managing Director at the Last Prisoner Project; Dr. Laura Garius, Policy Lead at Release; and Denzel Uba, an individual impacted by criminal cannabis prohibition.

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TOWIE star Amy Childs launches CBD range in honour of Jorja Foundation

The product range sees a portion of the proceeds going to the Jorja Foundation.

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Amy Childs at the launch of her new CBD range, Jorja Botanicals

TOWIE star Amy Childs launched her new CBD range this week, with a star-studded event that shone a spotlight on the story of six-year-old Jorja Emerson.

Amy Childs was joined by former Love Islanders, Amy Hart and Cara Delahoyde-Massey, alongside her  co-stars, Frankie Essex, Tom Skinner, Carina Lepore, Saffron Lempriere and Mark Ferris, for a heart-warming event celebrating the launch of her new CBD Infused beauty range, Jorja Botanicals.

The signature collection sees a portion of the proceeds going to the Jorja Foundation, which was set up in honour of six-year-old medical cannabis patient, Jorja Emerson.

The event saw The Only Way Is Essex star Frankie Essex, break down in tears as she heard Jorja’s story. Frankie, who gave birth to twins four weeks ago, wiped her eyes when Robin Emerson, Jorja’s father, showed videos of the life-threatening seizures his daughter was suffering before they discovered medical cannabis

Love Island star, Amy Hart has since taken to Instagram to spread the word about the latest political campaign that sees Childs and Emerson petitioning to make medical cannabis more widely available on the NHS

The Jorja Botanicals range was inspired by Jorja, who was diagnosed with a rare chromosome abnormality called 1q43q44 deletion, which has a side effect of life-threatening seizures. Her illness resulted in her being admitted to intensive care on two separate occasions, where Robin was told that she may not make it.

jorja botanicals

TOWIE stars joined Amy Childs for the launch of her new CBD range

To save his daughter’s life, Emerson knew that he had to dig deep and find a treatment that would not only help Jorja but ultimately go on to help others.

At the time it was still illegal to prescribe cannabis in the UK. Emerson joined the campaign to see medical cannabis legalised in the UK in November 2018, and Jorja’s was among the first children to be legally prescribed medicinal cannabis.

In 2021 he went on to create the Jorja Foundation – a charity set up to help other families and children going through the same battles that Robin had to face.

The Jorja Foundation’s core principles are to fund special needs equipment that is not funded through the health system, fund family counselling, private appointments and tests when a second opinion is needed, as well s cannabis-based treatment for children in the UK and to continue to campaign and educate for wider NHS access in the UK for cannabis-based medications.  

Childs commented: “When I saw Robin & Jorja’s story on social media it broke my heart.

As a mum, I couldn’t imagine the pain of being told to take my child home to say goodbye to them. I love that Robin has fought for Jorja & is now helping other families with the Jorja Foundation. 

“I’m so happy that I can help the foundation by being the Creative Director of Jorja Botanicals. We have created some beautiful products for the whole family to enjoy. We will be donating a percentage of the proceeds to the foundation so that we can help as many families as possible. ”

 Emerson added: “ This is the fruition of a lot of hard work over many months and I am extremely proud to launch what is the first family brand in this category. In the coming weeks, we will also be launching a ‘parent’ focused cosmetic range in partnership with our creative director Amy Childs and our premium line of tincture oils.”

 

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South Africa launches first trial of cannabis for chronic pain

The study will test whether cannabis can replace opioids in the management of chronic pain.

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South Africa’s first cannabis trial has launched after initial results “show promise” for the treatment as a replacement for opioids.

The Pharma Ethics Observational Study is led by Biodata, a subsidiary of Labat Africa, and will test whether cannabis can replace opioids in the management of chronic pain.

The study will involve 1,000 participants who have been taking opioids for pain management for at least three months and are prepared to switch to cannabis as an alternative.

Biodata is the brainchild of Dr Shiksha Gallow, a cannabis clinician and the principal investigator in the trial which took over 18 months to get official clearance.

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Dr Gallow said the trial is set to be ground-breaking as South Africa’s first real-world study of medical cannabis. Researchers predict that it will provide much-needed insight into the link between cannabis genetics and patient outcomes.

Dr Gallow told Cannabiz Africa: “We are currently recruiting patients, and data-capturing all the questionnaires and feedback from the patients for the live Study. It has been fairly slow. However, more options have been introduced, as suggested by the patients in the pilot study.

“The pilot results of the study were very promising, as it showed 98 per cent of the patients have some sort of pain relief from the cannabis.

“We were able to wean these patients off their opioid treatment. In the pilot group of patients below the age of 55, it was shown this group preferred to smoke cannabis and patients older than 55 years preferred oil. The patients who smoked the cannabis had relief almost immediately, while the oil took some time to alleviate their pain.”

“Once we reach the sample size required and all of the relevant data has been collated, the results of the study will be published. We have currently renewed this study for another year, due to the initial slow uptake of research participants.”

Patients can apply to be research participants through the Biodata website.

Labat is expanding its footprint over the next few months with the introduction of CannAfrica kiosks in major shopping malls.

The company believes these will be the “ideal locations for physical sign-up points for the study”.

Labat said the kiosks will also serve as Biodata dispensaries and is engaging with a number of vape stores to do the same, although these would have to be subject to South African Health Products Regulatory Authority’s pharma-ethics requirements.

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