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CBDA – is it an under-appreciated cannabinoid?

CBDA, the precursor to CBD, is often dismissed under the false assumption that it is an inactive cannabinoid

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CBDA is often dismissed as an inactive cannabinoid, but its benefits may be an under-appreciated

CBDA – the precursor to CBD – is often dismissed as an inactive compound, but its benefits may be under-appreciated, writes Laurence Brown of BROWN’s CBD.

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Out of the hundreds of biologically active compounds produced by the hemp plant, CBD is certainly the star of the show for health and wellbeing. But CBDA, the precursor to CBD, is often dismissed under the false assumption that it is an inactive cannabinoid.

At BROWN’s CBD, we found that oils retaining at least some CBDA seemed to outperform 100 percent decarboxylated oils. Anecdotal feedback from customers and consensus in certain Facebook groups also seemed to suggest this, which peaked our curiosity to dig a little deeper.

What is decarboxylation?

For those of you who don’t know, decarboxylation is a heat treatment that converts natural acidic cannabinoids (CBDA,THCA) into their neutral forms (CBD,THC). The temperature generally needs to be higher than 110 C, but decarboxylation will also happen naturally over long periods of time.

Decarboxylation is deemed to be necessary in order to increase a cannabinoid’s ability to interact with our cannabinoid receptors. These receptors are present throughout the body and are usually activated by endogenous cannabinoids (cannabinoids produced naturally by the body).

CBDA is the precursor to CBD

Is CBD really better?

But studies have demonstrated that CBDA can interact with certain receptors up to 100x more effectively than CBD. Furthermore, CBDA has been found to be four times more bioavailable than CBD, meaning that four times more CBD can be used by the body.

One could theorise that the people getting the best results with CBDA are the people whose issues are associated with these specific receptors. However, due to the lack of research around CBDA, it’s difficult to know for sure.

Another possibility is that as products containing CBDA have undergone less processing than heated oils, they may contain higher levels of certain cannabinoids, terpenes, and flavonoids that may contribute to the entourage effect. Which relates to greater efficacy thanks to a synergistic effect of multiple plant compounds combined.

Given that a recent study found CBDA blood levels to be 14 times higher when administered in a full spectrum extract when compared to an isolated form, this is certainly within the realm of possibility.

It’s worth noting that results can vary from person to person, so while some people have good results with CBDA, for others it may do nothing at all.

Commercially complicated

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Perhaps one of the key pitfalls that has made CBDA a castaway cannabinoid is its instability. As mentioned earlier, CBDA will naturally convert to CBD over time.

cbda capsules

This makes it a less attractive option for those looking to profit from the compound, and without a view of profit, it’s more complicated to get funding for clinical research. This instability also reduces its chances of it being approved by certain regulations, such as the Novel Foods act.

If you are interested in seeing if CBDA could be a valuable addition to your cannabinoid regime, we recommend giving our full spectrum hemp capsules a try. 

As these are made with 100 percent raw hemp, they naturally contain high levels of CBDA and every other compound produced by the hemp plant.

Don’t forget to consume them with a meal to boost their bioavailability.

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Combining CBD and CBG for the ultimate entourage effect

How much do you know about the 120 different cannabinoids in the cannabis plant? Browns CBD explains how CBD and CBG combine to offer different benefits

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The plant actually produces over 120 cannabinoids with some being equally as impressive for certain issues. Browns CBD explains how CBG and CBD combine for the ultimate entourage effect.

By now you will have surely heard of CBD – the hemp-derived compound that has a plethora of health benefits and is incredibly safe to use.

Another important cannabinoid is CBG (Cannabigerol). This cannabinoid is commonly referred to as the ‘mother of all cannabinoids’ as it is the original molecule that most other cannabinoids are synthesized from.

In simple terms, hemp produces CBGa (the acidic form of CBG) in earlier stages of growth which is then converted within the plant into cannabinoids such as THCa, CBDa & CBCa. This can be seen in the diagram below.

CBD and CBG: a diagram showing the different cannabinoids

CBG tends to be more expensive than CBD due to the fact that most varieties of hemp yield very low levels of CBG. And crops need to be harvested earlier to obtain significant levels of CBG for extraction. However, new CBG rich varieties of hemp are being developed to achieve greater yields.

CBD and CBG benefits

Studies on the benefits of CBG are fairly limited when compared to those of CBD, but there is some very promising preliminary evidence. Anecdotally, we have found customers to be very impressed with its calming effects on a range of issues.

CBG interacts with the endocannabinoid system differently from CBD. For those of you who don’t know, the endocannabinoid system is a significant bodily system made up of endocannabinoids, cannabinoid receptors and enzymes. This system is involved in the proper maintenance of a wide range of bodily functions.

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CBD indirectly interacts with these receptors, whereas CBG directly acts upon them. It is through this differentiation of interaction that we believe CBG can have different effects from CBD. A quick search on Google will highlight what these can be.

CBD and CBG: A brown bottle of CBD and CBG oil

Our CBG Hemp Oil is rich in CBG, but also in CBD. It has a 1:1 ratio of CBG to CBD in order to have the most significant impact on the endocannabinoid system. Furthermore, it contains both CBD and CBG in its acidic forms and a wide range of additional cannabinoids and terpenes.

Due to the huge variation of compounds within this product, it tends to have more pronounced effects than standard CBD oils of the same strength. Customers tend to be surprised at just how effective it is with the seemingly low 3 per cent concentration.

We believe this is due to the ‘entourage effect’ which is a phenomenon where compounds interact synergistically which results in stronger effects for the user. This has been demonstrated in several studies.

If you are interested in learning more about our CBG Hemp Oil and other effective products, head over to our website today – www.brownscbd.com

Read more: CBD guide – what’s the best way to take CBD?

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Study shows legalisation has no adverse effects on neonatal health outcomes

The team of researchers assessed the influence of statewide cannabis liberalisation policies on newborn health

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Neonatal: A baby holding a person's finger

A new study on the effects of legalising cannabis for adult or therapeutic use shows no adverse effects on neonatal health outcomes at the population level.

The neonatal study was published in the Journal of Health Economics and shows that legalising cannabis for adult use is not associated with adverse effects on neonatal health outcomes.

The team of researchers from Columbia University, University of North Carolina and Indiana University assessed the influence of statewide cannabis liberalisation policies on newborn health over 12 years starting in 2007.

They discovered that the proportion of maternal hospitalisations from cannabis use disorder increased by 23 percent in the first three years of legalisation with larger percentages in states where commercial sales were allowed. This was accompanied by a decrease of 7 percent in tobacco use disorder hospitalisations.

Legalised cannabis was not associated with any significant changes in newborn health according to the study. Medical cannabis laws had no statistically significant effect on maternal substance use disorder hospitalisations or on newborn health.

Neonatal health

The authors wrote: “There is no statistically significant effect of medical cannabis laws on the proportion of newborn hospitalisations with prenatal exposure to noxious substances, neonatal drug withdrawal syndrome, fetal alcohol syndrome, slow growth, respiratory conditions, feeding problems, congenital abnormalities, low gestational age, low birth weight, or very low birth weight. Likewise, recreational cannabis laws appear to have no effect on these outcomes.”

They concluded, “In absolute numbers, our findings implied modest or no adverse effects of cannabis liberalisation policies on the array of perinatal outcomes considered.” However, they cautioned, “Our null findings do not refute nor support an argument that prenatal exposure to cannabis has negative effects on newborn health outcomes, but rather that state cannabis liberalisation policies are not associated with net changes at the population-level that are statistically detectable or economically meaningful.”

READ MORE  UK to trial cannabis-based drug in treatment of brain tumours

Neonatal studies

Other studies assessing the potential effects of cannabis use during perinatal health are inconsistent. Some studies link cannabis use to lower birth weights but failed to adjust methods to account for contributing factors such as tobacco smoking.

A study conducted during the pandemic revealed that cannabis use among pregnant women has increased during lockdown.

Researchers from Kaiser Permanente analysed figures of pregnant women consuming cannabis in Northern California during the pandemic to the numbers from the previous year.

The study involved analysing urine toxicology tests of more than 95,000 women having their first prenatal visit in Northern California Kaiser Permanente. They collected the tests between January 2019 and December 2020 before comparing them to tests from 15 months prior to the start of the pandemic. The results showed a 25 percent increase in the rate of cannabis consumption. Prior to the pandemic, the rates of pregnant women using cannabis were at 6.75 percent. This rose to 8.14 percent during the lockdown.

Read more about this study here

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International Day of the Girl: Five inspiring women in sport who use CBD for recovery

These women are not just using CBD to train better and recover faster but are becoming successful entrepreneurs in the field.

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Sports: A woman stretches her arms above her head while warming up

To mark International Day of the Girl, we list five inspiring women in sport who use CBD to help with their training and sports injuries

What is the International Day of the Girl? 

The day was started by the United Nations in 2012 as a way to highlight and address the needs and challenges girls face throughout the world. The aim is to promote training and education to create successful women. It helps to empower girls and support them.

Female athletes in a variety of different sports are turning to CBD to help with recovery from injury. Their strength, determination and athleticism make them inspiring. As the CBD industry grows, more athletes are not only using CBD but becoming business entrepreneurs by investing in, partnering with and developing sports brands.

Sports: A banner advert for IMPACT CBD showing a bottle of CBD oil and a torso of a woman

 

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Gabby Douglas

Gabby Douglas was the first African-American gymnast in Olympic history to become the Individual All-Around Champion. She was also the first American gymnast to win gold in the Olympic individual all-around and team competitions.

Gymnastics is a notoriously demanding sport that sees most athletes retire in their early 20s. The most common injuries are to the knees and ankles. This can be caused by landing and dismount activities and can include Anterior Cruciate Ligament (ACL) Injury. Achilles Tendon Injury. Studies show that Female gymnastics may suffer more major injuries from the sport than men. They commonly undergo surgery after injuries at a rate of 24.4 percent in comparison to 9.2 percent of men.

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Douglas said: “My experiences in using CBD have led me to believe that I could have been more pain-free throughout my gymnastics career if CBD had been allowed. I am glad that athletes across all Olympic sports will now have the opportunity to use these products and hopefully experience their benefits.”

Douglas is also thought to be an investor in the CBD industry. She partnered with skier Bode Millar to invest in a CBD company, Motive CBD.

Megan and Rachel Rapinoe

Megan Rapinoe is possibly the best known female athlete who uses CBD. She also co-owns. a CBD company, Menhi, with her sister, Rachel Rapinoe. She is also an outspoken LGBT+ activist.

US footballer Megan is a two time World Cup Champion, 2019 Best FIFA Women’s Player of the Year and Gold Medalist. She is said to rely on CBD to help her stay balanced, manage chronic pain, and get better sleep. Her twin sister Rachel also comes from a sports background as a former American soccer player who played as a midfielder and forward. She played for Stjarnan Women in Iceland and the United States women’s national under-23 soccer team.

The sisters developed Menhi after discovering CBD post-recovery from football matches and training. Common injuries for footballers can include ankle or knee sprains, quad, hamstring and groin strains.

 

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Ashley Jade

Ashley Jade is a dancer and choreographer based in Seattle. As well as using CBD for her recovery, she has partnered with Just CBD to promote their range of gummies.

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She has spoken on social media about the difficulties of being a dancer with rheumatoid arthritis and how CBD helps her to cope with the chronic pain it causes.

She posted: “Integrating CBD into my daily self-care routine keeps me in my body and ready to move. It’s been difficult navigating a dance career living with a rheumatoid arthritis condition that causes chronic pain in my spine and pelvis. I haven’t woken up without pain in over 3 years but when I began the use of CBD for pain management, I felt my overall inflammation level soothe significantly. I honestly wouldn’t be dancing the way that I do now without access to the therapeutic benefits of CBD.”

 

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Mindy Chen

Mindy Chen is a powerlifter. She is currently transitioning into the running world. She came in second at the World Powerlifting Championships 2016 in the 52g Category. She has posted on social media about using CBD drinks while training in different sports. Mindy partnered with Life Aid to promote its range of CBD waters.

She uses CBD to help with the tension in her muscles which has developed throughout her weightlifting and sports career. Powerlifting is a strength sport that consists of three attempts at maximal weights on three different lifts. This includes squatting, bench pressing and deadlift. The most common injuries that occur over time are shoulder impingement, lower back injury and also patellofemoral pain (knee).

 

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Alex Morgan

Alex Morgan is best known for being one of the youngest members of the U.S Women’s National Soccer Team. She won a Gold Olympic Medal against Japan in the Summer Games in 2012 and co-captained the U.S team to victory in the FIFA World Cup 2019.

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She uses CBD topicals or tinctures for help with injuries from her sport.  but she helped to co-found a new brand that offers a range of products geared towards athletes.

Read more about the brand launch here

In a statement on the Just Live site, she says she uses CBD to unwind and also to help with shoulder pain. “I have a convincing experience when I sprained my shoulder and had a match 3 days later. I’ve used CBD on muscle aches and pains ever since. I also have a hard time winding down after a game and have found that I am able to go to sleep earlier after a game and feel more rested when I have a CBD capsule or tincture following the match.”

Read more: Justin Bieber launches cannabis line with a charitable focus

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