Medical cannabis experts Kanabo break down the confusing terminology of vaping CBD and explain everything we need to know.
From e-cigarettes to vaping, vaporization is a term with many aliases. It’s no wonder some people find it confusing
For some, it’s a hobby. For others, it’s a way to cut back on smoking cigarettes, and for many, it’s the only way to get a fix of CBD, fast.
The world-class medical cannabis research group, Kanabo, is behind the first-ever medical grade vaporizer. So, we asked their experts to tell us everything we need to know about CBD and vaporization.
First, what is vaporization?
When you inhale from a vaporizer, the liquid in the cartridge is converted into vapour at a high temperature. This is the process of vaporization. In standard e-cigarettes, this happens via a wick and atomizer set-up, however, Kanabo uses next-generation technology to guarantee a more consistent flow and temperature.
Compared to the many other ways of taking CBD, vaporization is extremely effective at delivering CBD to the pulmonary tract, providing precise dosing and rapid onset so that it can serve the Endocannabinoid system quickly.
Isn’t vaporization the same as smoking?
This is a very common misconception. The short answer is no.
While the action of raising a device to the mouth mimics the same action smokers will be used to, vaping is much safer and less harmful to your health. How? Firstly, vaporization doesn’t require combustion. The particles in the liquid are heated at a much lower temperature.
The result is a clean, carcinogen-free experience.
Add to that the lack of nicotine and tobacco used in CBD vaporization and this delivery method really stands out compared to smoking and using regular e-cigarettes. Not only does this provide for a better CBD experience, but it also removes the possibility of addiction.
This makes vaporization attractive to those who are embarking on a smoke-free journey who also want to experience the benefits that CBD has to offer.
In the UK, vaporization has been endorsed by Public Health England since 2015. That year, in a landmark review, the government body backed vaping publicly, saying it was ‘around 95 per cent less harmful than tobacco’.
What happens in the body when you vape CBD?
To explain the process fully, let’s take the Kanabo VapePod device as an example.
When you inhale from the VapePod, the CBD and terpene-rich oil held in the cartridge is converted into vapour. This happens at a lower, safer temperature compared to your average e-cigarette.
From the mouth, it travels to the throat and down into the lungs where it is dispersed into the bloodstream via the pulmonary tract. From here, CBD interacts with the Endocannabinoid system. This action happens in seconds, with the active ingredients getting to work in minutes.
If you think of it in terms of your own body, with every inhale, your body is receiving vaporized cannabinoids.
Compared to taking oil drops under the tongue or using CBD capsules, this method avoids the body’s natural processes of breaking substances down, which often damages some of the active ingredients.
Instead of letting this happen, vaporization bypasses these processes providing a quicker delivery of CBD when you need it most.
This is a precise, science-based, no-nonsense approach to getting a metered amount of CBD, and feeling the difference fast. So much so, it is estimated that up to 75 per cent of the active ingredients in the product are absorbed and effective in the body.
How do you use a vaporizer with CBD?
Let’s stick with the VapePod device from Kanabo for this example as it is the easiest, no-nonsense approach to this scenario.
First of all, you will need a device and a compatible cartridge. Thankfully, Kanabo has produced three carts – Reload, Repair and Relax – each measuring 0.5ml of fluid.
Once you have chosen the cartridge that best suits your mood and how you’re feeling, you will simply need to draw from the device. There are no confusing settings to play with, no buttons that need to be pressed, it really couldn’t be simpler.
To let you know that it’s working, the device will gently vibrate when you begin the draw from it. Then, as you inhale, it will cut out after 1.5 seconds, providing a perfectly measured dose of 1mg CBD every time.
The VapePod device can measure and deliver more than 300 doses with each cartridge lasting around six to eight weeks! When you’re not using your new vaporizer, it can be discreetly stored in a pocket or purse. It charges wirelessly too, taking the chore out of charging.
How do I know if vaping CBD is right for me?
If you’re a regular smoker, or you are on a smoke-free journey, and you want to try CBD, vaporization is for you.
Many who suffer from chronic pain are also attracted to vaporization when it comes to taking CBD. As the first-ever medical-grade vape device, the VapePod by Kanabo, is a popular choice for many, due to the rapid onset of CBD, ease of use and metered dosing the device has to offer. In other words, there is no waiting around to feel the effects, and you know exactly how much CBD you are putting into your body every time you inhale.
The verdict on vaporization
To recap, there are many ways to take CBD. However, no two ways are the same and in some instances, the body’s natural processes – the first-pass metabolism – can destroy some of the active ingredients, lessening the effects and leading to disappointment.
Vaporization gets around these issues by delivering CBD via inhalation, into the lungs and the pulmonary tract. This has been highlighted in various studies by international researchers looking towards a better future for CBD delivery.
New studies examine effects of THC and CBD on stroke
New data suggests both positive and negative effects of cannabis in stroke patients
A new study has shown that pre-treatment CBD may have a neuroprotective effect in stroke patients.
The study aimed to investigate the effect of CBD on oxidative stress and cell death which occurs in ischemic stroke patients.
It revealed that the cannabinoid may reduce the destructive effects of cell damage associated with stroke.
Ischemic strokes are the most common type of stroke. They occur when a blood clot blocks a flow of oxygen or blood to the brain. This takes place in arteries that have been narrowed or blocked over time by fatty deposits (plaques). The most common symptoms of a stroke include facial drooping on one side, not being able to lift your arms and slurred speech.
If this occurs, it is vital that a person be taken to the emergency room immediately.
The National Institute of Health Care and Excellence (NICE) estimate that there are around 100,000 strokes every year in the UK. It is also thought that 1.3 million people live with the effects of a stroke.
Stroke recovery and CBD results
The Study showed that CBD reduced the amount of infarction in those samples which had been given the cannabinoid. Infarction refers to the death of tissue as a result of a lack of blood supply and is commonly due to a blood vessel being obstructed or narrowed.
There were also differences in malondialdehyde level (MDA) – a common marker of oxidative stress – between the brains of the CBD group and the vehicle group.
It also revealed that CBD may help to protect tissue by preventing further damage.
THC and stroke risk
According to findings, cannabis consumers who experience a stroke known as an aneurysmal subarachnoid haemorrhage (aSAH), are twice as likely to develop further complications.
An aSAH occurs when a weakened blood vessel bursts on the surface of the brain leading to bleeding between the brain and tissue that covers it. It can result in neurological disabilities, long-term slurred speech or even death. It is estimated that aSAH affects around eight people per 100,000 of the population each year, accounting for six per cent of first strokes.
The study by the American Stroke Association suggested there is twice the risk of developing delayed cerebral ischemia for cannabis consumers. The researchers analysed data from 1,000 patients who had received treatment for bleeding over a 12 year period. In the group of participants, 36 per cent developed cerebral ischemia and 50 per cent had moderate to severe disabilities.
When comparing the results of patients who tested positive for THC with those who did not, they found cannabis consumers were 2.7 times more likely to develop cerebral ischemia. They were also 2.8 times more likely to develop long-term moderate to severe physical disabilities.
However, compared to those who tested negative for THC, the cannabis group did not have larger aneurysms, higher blood pressures or worse stroke symptoms when admitted to the hospital. They did not have any higher cardiovascular risk factors than the negative group.
Researchers are now conducting further studies in which they hope to better understand if THC can impact aneurysm formation and rupture.
New study shows CBD may prevent Covid-19 infection
Researchers are calling for more trials to determine if CBD could be a preventative or early treatment for the virus.
Researchers are recommending clinical trials to examine if CBD could help to prevent Covid infection after more positive findings have been published.
Researchers from the University of Chicago have reported that CBD may stop the infection of Covid-19 by blocking its ability to replicate in the lungs.
A number of cannabinoids including CBD and THC were tested along with 7-Hydroxycannabidiol (7-OH-CBD) which is thought to be produced when cannabidiol is processed by the body.
The study found that CBD showed a significant negative association with SARS-CoV-2 positive tests in a national sample of patients who were taking high doses of CBD, prescribed for epilepsy.
As a result of their findings, researchers are calling for more clinical trials to determine whether CBD could eventually be used as a preventative or early treatment for the virus.
Covid and CBD study
Researchers treated human lung cells with a non-toxic dose of CBD for two hours before exposing the cells to SARS-CoV-2 and monitoring them for the virus and the viral spike protein.
They found that, above a certain threshold concentration, CBD inhibited the virus’ ability to replicate.
Further investigation found that CBD had the same effect in two other types of cells and for three variants of SARS-CoV-2 in addition to the original strain.
CBD did not affect the ability of SARS-CoV-2 to enter the cell. Instead, CBD was effective at blocking replication early in the infection cycle and six hours after the virus had already infected the cell.
Like all viruses, SARS-CoV-2 affects the host cell by hijacking its gene expression machinery to produce more copies of itself and its viral proteins. This effect can be observed by tracking virus-induced changes in cellular RNAs. High concentrations of CBD almost completely eradicated the expression of viral RNAs.
When it came to the other cannabinoids, CBD was found to be the only potentially potent agent. There was no or limited antiviral activity noted by the similar cannabinoids including THC, CBDA, CBDV, CBC or even CBG.
Marsha Rosner, PhD, professor and senior author of the study said it was a completely unexpected result, she commented: “CBD has anti-inflammatory effects, so we thought that maybe it would stop the second phase of COVID infection involving the immune system, the so-called ‘cytokine storm.’ Surprisingly, it directly inhibited viral replication in lung cells.
She added: “We just wanted to know if CBD would affect the immune system. No one in their right mind would have ever thought that it blocked viral replication, but that’s what it did.”
The researchers do caution that this is not possible with commercially available CBD. The CBD tested was high-purity and also medical grade.
However, Rosner cautioned: “Going to your corner bakery and buying some CBD muffins or gummy bears probably won’t do anything. The commercially available CBD powder we looked at, which was off the shelf and something you could order online, was sometimes surprisingly of high purity but also of inconsistent quality. It is also hard to get into an oral solution that can be absorbed without the special, FDA-approved formulation.”
CBD and Covid studies
This is the second study to be released showing the potential for cannabinoids in Covid management and prevention.
A study by Oregon State University has revealed that the compounds cannabigerolic acid (CBGA) and cannabidiolic acid (CBDA), may have the ability to prevent the virus that causes Covid-19 from entering human cells.
Researchers and scientists, led by Richard van Breedan, found that a pair of cannabinoid acids bind to the SARS-CoV-2 spike protein, blocking a step in the process the virus takes for infection.
Targeting compounds that block the virus-receptor interaction has been helpful for patients with other viral infections such as HIV-1 and hepatitis.
The researchers and scientists identified the two cannabinoid acids through a screening technique, developed previously in van Breeman’s laboratory. The team also screened different botanicals such as red clover, hops, wild yam and three types of liquorice.
Partner of Irish politician “six years seizure free” faces charges over medical cannabis use
John Montaine uses medical cannabis to manage his epilepsy – and is said to be six years seizure free.
The partner of a sitting Irish TD is contesting charges of cannabis possession, saying he uses it medicinally to manage his epilepsy.
John Montaine, who is the partner of Clare Sinn Fein TD Violet Ann Wynne, was charged with the alleged illegal possession of cannabis on February 11, 2021, at his family home, the Irish Independent reported.
Mr Montaine contests the charges and his partner Deputy Wynne has previously spoken publicly about how he uses cannabis medicinally to manage his epilepsy.
Speaking after the initial court hearing in November, Deputy Wynne said in March her partner would be “six years seizure free”.
She went on to say that it has improved his quality of life “100 per cent, without a doubt”.
“There was always some kind of issue – say John having a number of fits within the one month or losing teeth or suffering with severe migraine, but since John has been using the medicinal cannabis, he has had a better quality of life,” Deputy Wynne told the Independent.
She added: “It has also freed myself up. John would have been on disability allowance and I would have had to have been his carer but since using the medicinal cannabis, he doesn’t suffer from any of those issues any longer.”
Medical cannabis is legal in Ireland, but access to a prescription is limited.
Despite legislation being signed off in 2019, Ireland’s Health minister Stephen Donnelly only announced funding for it in January 2021, with the programme only becoming fully operational in November.
Four cannabis-based medicines are expected to be available through the MCAP, to people living with one of three qualifying conditions. These include intractable nausea and vomiting associated with chemotherapy, severe treatment-resistant epilepsy and spasticity associated with multiple sclerosis (MS).
Mr Montaine’s solicitor appeared in Kilrush District Court on behalf of his client this week, where his case was adjourned until 15 March.
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