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How do CBD and THC affect sleep?

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CBD is known to help aid sleep, but what about THC?

A good night’s sleep leaves us feeling rested and refreshed, ready to face the day ahead. But, for too many people, that’s nothing more than a pipe dream.

Insomnia is increasingly common, and, while it is often assumed to be a short-term response to stress or external factors, around 30 per cent of sufferers display chronic symptoms.

Chronic insomnia is characterised by sleep disturbances, such as difficulty falling asleep, maintaining sleep, or inability to return to sleep on waking, happening at least three nights per week and for at least three months. Such disturbances are often coupled with significant daytime impairments in social life, function levels and educational achievement; indeed, it is often the effects of the sleeplessness on daily life that prompt a sufferer to seek treatment.  

While there are steps we can all take to improve our sleep, such as regular exercise, reducing stress and good sleep hygiene, sometimes sufferers turn to over-the-counter medications to help them drift off. However, these have a number of significant side effects, and are not seen as a sustainable solution.

Meanwhile, a growing body of research has found that CBD can have a positive effect on sleep, both by aiding relaxation and also by stimulating CBD receptors in the part of the brain responsible for maintaining sleep cycles.

However, most of the previous studies have focused on CBD as a standalone compound – until now…

A recent ongoing study reported in the British Medical Journal is investigating the effects of both CBD and THC (the psychoactive element of cannabis) on sleep and the resulting function levels the following morning. 

The research aims to test the safety and efficacy of an oral oil solution containing 10mg of THC and 200mg CBD, and will use 20 participants diagnosed with chronic insomnia disorder. 

The participants, who are all aged between 35 and 60, were recruited over an 18-month period and

each received both the active drug and matched placebo during two overnight study assessment visits. 

The researchers’ primary aim is to assess total sleep time and wake after sleep onset assessed via polysomnography. 

In addition, they will use MRI technology to examine the brain activation of the participants during sleep and wake periods, comparing the effects of CBD/THC versus the placebo. 

Next-day cognitive function, alertness and simulated driving performance will also be investigated.

The study authors said: “Insomnia is a highly prevalent and costly condition that is associated with increased health risks and healthcare utilisation. 

“Anecdotally, cannabis use is frequently reported by consumers to promote sleep. However, there is limited research on the effects of cannabis on sleep and daytime function in people with insomnia disorder using objective measures. 

“This proof-of-concept study will evaluate the effects of a single dose of an oral cannabis-based medicine on sleep and daytime function in participants with chronic insomnia disorder.”

As we have seen, previous studies have appeared to show a positive effect of CBD on sleep, and, while further research such as the above is needed, there is certainly an appetite amongst consumers for a natural, effective sleep aid.

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Lifestyle

What are CBD patches and do they work?

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Transdermal patches are a relatively new concept in the CBD world but they could be one of the most effective ways to reap the benefits, the team at Hapi Hemp explain.

Since CBD has become so popular it is now available in many different forms – from tincture oils to edibles to capsules, CBD teas and even a CBD superfood mix.

CBD patches are not just another item on a list nor are they a fad, these patches are not only unique, but they are also smart and incredibly effective.

Even though these patches are extremely simple, the actual ‘how’ is a little more technical, which we explain below.

What are CBD patches?

Transdermal patches may be relatively new in the world of CBD, but the concept has been around for years. They work in a similar way to nicotine or hormonal patches, with a few twists that ensure the patch can effectively deliver CBD into your bloodstream.

The Hapi CBD patch is made from organic hemp extract, taking goodness from this wonderful plant ensuring the full benefits in a THC free transdermal format.

One of the benefits of using CBD patches is the fast delivery of CBD into the bloodstream. The CBD doesn’t have to go through other bodily processes, so you start feeling the effects in a matter of minutes after attaching the patch to your skin.

How do CBD patches work?

CBD patches pass CBD directly into our skin cells. Because our cells are made of lipids, and cannabinoids are also lipids, CBD readily diffuses through our cells, eventually making the way to our blood vessels. In other words, they deliver cannabinoids into your bloodstream through the skin, which allows the CBD to reach your endocannabinoid system, where it binds with CB1 and CB2 receptors to produce a variety of beneficial effects.

The Benefits of CBD Patches

One of the benefits of using our CBD patches is the fast delivery of CBD into the bloodstream.

The CBD doesn’t have to go through any processes throughout the body, so you start feeling the effects within minutes of applying the patch.

There is also the added bonus of CBD activating the skin cells directly (without needing to travel through the blood), which can also be very beneficial for our skin.

CBD patches allow you to target specific areas of the body. For example, if you had a particular area you are thinking to use it, you could apply the patch directly onto that area, so it receives the direct full flow of CBD fast.

CBD patches allow for the steady and consistent delivery of CBD over the course of 24 hours and have the added bonus of a faster intense delivery.

Then the next day simply remove the patch and apply a new one. One day you may decide to apply the CBD patch to your arm, another day you may apply it to your shoulder – the choice is yours and you are in complete control.

Testers who have tried these patches have been surprised at just how effective they are.

One lady said: “The beauty of this is I can put it on where I want, I can stick it on my shoulder one day, then another I can stick it on my foot. I have decided that when I can finally go out I will pop it on my bunion before I put my heels on!”

Beyond efficacy and efficiency, our CBD patches offer one of the easiest and most effective deliveries of CBD.

The Hapi CBD patch comes in three different packs – a Six patch pouch, 18 patch pouch, 30 patch pouch – so you have the option to try first if you wish, however the feedback we have had back from our testers is remarkable.

Order online at www.hapihemp.co.uk

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Lifestyle

Is it safe to take CBD with other medication?

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Medical professionals can give you the best advice around taking CBD with your medication

With potential to ease symptoms in conditions such as fibromyalgia, insomnia, depression and many more, the use of CBD is rapidly rising.

But there’s one resounding question that needs to be taken into consideration before turning to the remedy – is it safe to take with other medication?

Considering the nature of the conditions many medicinal CBD users suffer from – chronic pain, mental health issues and so on – it’s likely they will already be taking prescribed medication to aid their symptoms before branching out into CBD. Therefore, it’s vital to understand the effects these remedies may have on each other.

When you take a medication, your body must metabolise – or break down – the substance. This ‘drug’ metabolism happens throughout various parts of the body, with the gut and liver playing a particularly big part in the breakdown.

In these areas, a family of enzymes called cytochrome P450 (CYP450) converts foreign substances so they can be easily eliminated from our bodies. However, some medications affect CYP450 by either slowing down or speeding up drug metabolism.

So, what does this mean in relation to CBD? This change in metabolism rate can alter how your body processes the medication or supplements – such as CBD – that you take, causing a drug interaction.

It has been found that CBD can interfere with the CYP450 family of enzymes, meaning the system can’t work as effectively to break down the medications in your system. In reverse, if the medication you are taking inhibits the enzymes, then your body will struggle to process the CBD as effectively.

This lack of breakdown can then lead to more medication in your system than intended – even if you take a recommended dose – or not enough of the medication to combat the health issue.

With this in mind, researchers are working to understand interactions and effects of specific medications and CBD.

For example, a study of 25 children with hard-to-treat epilepsy found that when patients were given both clobazam and CBD, there were elevated levels of the clobazam. This led them to conclude that while taking CBD and clobazam at the same time is safe, it’s important to monitor medication levels and any potential side effects.

Similarly, an investigation into adverse drug events (ADEs) between traditional anti-epileptic drugs and CBD found that the effective does of CBD was mostly well tolerated when co-administered with clobazam, stiripentol or valproate in adults, and that ADEs only occurred in patients for which there was no dosage titration.

Another area to consider before adding CBD to your supplement list is the potential ‘doubling-up’ impact it could have on existing side effects. While generally safe, CBD has been known to cause symptoms such as nausea and drowsiness in some users. Therefore, taking this with medications that cause similar symptoms may lead to an enhanced effect.

Ultimately, the consequences of CBD and drug interactions can depend on many factors, including dosage, age, health conditions and more. So, it’s important to consult your doctor or a medical professional if you intend to try CBD.

From there, your doctor should be able to advise whether it’s safe for you to proceed, whether to alter your dosage, and which product is likely to work best for your needs.

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Cannabis-based sleep product sales up 635% since COVID-19

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Cannabis shopping platform Ganja Goddess said the industry as a whole has shown signs of growth since the pandemic began

US sales of cannabis products that are marketed to help sleep, have increased significantly since the start of the pandemic as the industry continues to cultivate.

California’s online shopping, lifestyle and cannabis delivery platform, Ganja Goddess, announced key consumer and platform findings since the start of the COVID-19 this month.

The results revealed a sustained demand for cannabis delivery one year since the start of the global pandemic. 

Ganja Goddess’ key consumer and platform shifts include a 635 percent increase in revenue for cannabis products marketed to support sleep.

The industry as a whole saw a sustained 100 percent growth year-on-year, a 275 percent increase in revenue on 4/20, the largest day for cannabis delivery sales, shortly followed by a 200 percent increase in revenue on Cyber Monday, the second largest.

The platform also reported a 53 percent increase in conversion rates, which outperforms the average e-commerce conversion rate of one to two percent by more than 350 percent.  

During lockdown restrictions, both medical and recreational cannabis were considered essential services across the US, but were forced to shift to delivery or collection services. 

“With consumers spending more time at home than ever before while sheltering in place, cannabis delivery became a vital force in the industry,” said Ganja Goddess CEO Zachary Pitts.

“With cannabis deemed an essential service, the pandemic acted like rocket fuel for what was already a growing consumer trend headed for the mainstream. 

“In a year filled with challenges, we saw a surge in consumers placing orders for cannabis products marketed to help with sleep issues, highlighting one of the many health issues Americans are facing during the pandemic. 

Founded in 2011, Ganja Goddess offers statewide delivery services, online shopping and a curated online cannabis lifestyle experience that caters to consumers demands in California, the world’s largest cannabis market.

“The critical need for cannabis delivery remains at an all-time high. As challenges related to the pandemic continue, we are committed to serving the growing needs of cannabis consumers and patients across California.”

In the UK, research from a team at Southampton University found a sharp rise in the number of Britons suffering from insomnia and anxiety-induced sleep problems since the pandemic.

A paper published in the Journal of Psychopharmacology found that systemic acute administration of CBD appears to increase total sleep time and a review from 2017 echoed these sentiments, with researchers noting that preliminary research into CBD has found that CBD “may have therapeutic potential for the treatment of insomnia” and that it “may hold promise for REM sleep behaviour disorder and excessive daytime sleepiness”.

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