Charlotte’s Web collaborates on CBD/CBN sleep and anxiety study

New research will assess the potential of cannabinoids CBD and CBN for improving sleep and reducing anxiety.

Renowned CBD brand Charlotte’s Web is collaborating with the University of Colorado-Boulder’s REACH (Research and Education Addressing Cannabis and Health) Centre on a preclinical sleep and anxiety study.

The scientific investigation will use the company’s full spectrum hemp formulations with CBN (cannabinol), CBD (cannabidiol) and levels of THC below 0.3 percent to examine the impact on anxiety and sleep quality. 

There is limited preclinical or clinical data on phytocannabinoids other than CBD and THC, especially their effect at levels available in commercially sold hemp-derived CBD supplements. 

While there is some anecdotal evidence on the ability of CBN to help with sleep, there is little substantiated clinical or preclinical evidence to validate these claims. 

It is hoped that this study will inform future clinical initiatives to better understand how specific ratios of cannabinoids and different delivery formats are effective at supporting improved sleep quality and instilling healthier sleep patterns in humans.

Charlotte’s Web is the only hemp CBD brand supporting the University of Colorado REACH Centre’s milestone study.

“Charlotte’s Web is committed to advancing science on the benefits and safety of CBD and other hemp phytocannabinoids through rigorous scientific investigations such as this sleep and anxiety study,” said Tim Orr, senior vice president of Charlotte’s Web and president of its CW Labs division, which currently has more than a dozen scientific research studies underway. 

“We’re honoured to team up with CU’s REACH Centre to explore the potential impacts of full-spectrum hemp extract with CBD and CBN on anxiety and sleep quality.”

Monika Fleshner, PhD, Professor of Integrative Physiology, and a member of the Centre for Neuroscience at the University of Colorado-Boulder is the project lead, and this preclinical study will be conducted in her Stress Physiology Laboratory.   

“There is a great need for properly controlled experimental studies that are designed to test the potential neural and physiological impacts of hemp derived phytocannabinoids,” she commented.

“With support from CU REACH and Charlotte’s Web, our research will explore both the efficacy and mechanisms of how these substances can affect complex brain-mediated behaviour, such as disturbed sleep.”