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Isle of Man gives go ahead to grow medical cannabis

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The Canna Consultants founder said it was an ‘exciting time’ for the industry and the island

Leaders on the Isle of Man have backed a licensing system for the cultivation of medical cannabis on the island.

The Isle of Man’s parliament, Tynwald, voted unanimously on Tuesday 19 January to approve the regulations which will allow for the cultivation of medicinal cannabis. 

Medical cannabis grown on the island can now be exported to a global market, boosting the economy and creating potentially hundreds of employment opportunities. 

The island has set its sight on becoming a ‘centre of excellence’ for the cultivation of cannabis for medicinal use, with regulations allowing licences to be issued for the indoor cultivation of limited strength THC in a controlled environment.

The Gambling Supervision Commission (GSC) will be responsible for the granting of licenses and ensuring rules around quality and security within the sector are followed, after a transfer of power from the Department of Health in December 2020.

For the last year, London-based cannabis consultancy firm, The Canna Consultants have acted as exclusive consultants to the Isle of Man in the development of these regulations.

Welcoming the outcome, co-founder and director, Stephen Oliver, said it was an ‘exciting time’ for the industry and the island. 

Stephen Oliver, director of The London Canna Consultants

“We’re very pleased with the outcome, which is what we hoped for,” he told Cannabis Health.

“It’s a very exciting time for the island. We see it as providing huge opportunities for young people there, which have previously been limited.”

He added: “The island is very progressive and I think we’ll find that this is a staged implementation, they embrace the idea of becoming a centre of excellence of research and development.”

The first test crops and license applications are expected this year, with the production of the first of medicinal products from the island in the next two years. 

According to Oliver, the Isle of Man’s ability to offer longevity and security, have set it up to become a world leader in the sector. 

“We’ve seen huge acquisitions and licence applications across the globe, but one of the things the Isle of Man offers is a stable government, the ministers are all independent and have the ability to pass progressive laws,” he said

“People who want to cultivate cannabis want a secure regime, they want the longevity and security that’s offered with that. They don’t want to invest millions of pounds and then wonder whether or not in five or 10 years time that’s going to be removed.”

The Canna Consultants are now working with industry participants who wish to obtain licences on the Isle of Man to export medical cannabis to other countries in Europe.

Oliver also expects to see joint ventures between land and infrastructure owners and firms with more experience of indoor cultivation.

Although medical cannabis will still not be able to be accessed locally, the move is considered a step in the right direction. 

“Some of the kickback has been that this doesn’t allow people on the island to get access to cannabis medicines, but as we’ve seen, globally, all of these are stepped changes,” Oliver said.

“The important thing here is that containment of quality and being selective about the type of producers which can come to the island and looking at the creation of employment and opportunities.”

Will the move have a knock-on effect in the UK, where hemp farmers are still not permitted to utilise the flower or buds of the cannabis plant?

“I think it has to have a positive effect eventually, but I don’t expect it to happen overnight,” added Oliver.

“We saw the revolutionary access to medical cannabis two years ago, but this is not about a single piece of legislation it’s about an attitude. 

“We’ve got the Channel Islands, which are also very progressive and where we’ve seen recent investment in medicinal cannabis facilities there.

“I think the UK government is going to have to react at some stage.”

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Charlotte’s Web announces long-term study into effects of CBD

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Charlotte's Web is the leading CBD brand in the US

The company behind renowned CBD brand Charlotte’s Web has teamed up with leading scientific researchers to examine the cannabinoid’s effects on physical and mental health.

Charlotte’s Web Labs (CWL), the research arm of the renowned CBD producer, has announced a long-term scientific collaboration with McLean Hospital, a Harvard Medical School affiliate.

Two distinct clinical trials will investigate the efficacy of a custom-formulated, hemp-derived high-CBD product, with results to be published in 2022.

The trials will be overseen by lead researcher Dr Staci A Gruber, Ph.D, associate professor of psychiatry at Harvard Medical School and director of the MIND program at McLean Hospital in Belmont, Mass.

Harvard Medical School’s associate professor of Psychiatry, Dr Staci Gruber, PhD (CNW Group/Charlotte’s Web Holdings, Inc.)

Dr Gruber’s Marijuana Investigations for Neuroscientific Discovery (MIND) Program, established in 2014, is the first of its kind, and is dedicated to studying the long-term impact of cannabis and cannabinoids for medical and adult use which utilises various clinical and cognitive tools as well as multimodal neuroimaging techniques.

MIND utilises valid, robust research models and supports numerous projects designed to address the impact of medical cannabis on important variables such as cognition, brain structure and function, mood, conventional medication use, quality of life, pain, sleep, and other health-related measures.

Through observational longitudinal investigations, survey studies, and clinical trials of custom-formulated cannabinoid products, MIND aims to examine the unique effects of cannabis and its constituents to determine the efficacy of cannabinoids for specific conditions and diseases and to clarify the overall impact of cannabinoid-based treatments on physical and mental health.

Dr Gruber is also conducting a number of other studies, including a longitudinal observational study of veterans who use Charlotte’s Web products.

Charlotte’s Web is the number one CBD brand in the USA and distributed through more than 22,000 retail locations, select distributors and online.

CWL is the research and development division of Charlotte’s Web, with an aim of advancing science around hemp-derived phytocannabinoids, terpenes and flavonoid compounds.

“We are honoured to be working with Dr. Gruber, Harvard Medical School and McLean Hospital on these important clinical trials,” said Tim Orr, president of Charlotte’s Web’s CW Labs division.

“Charlotte’s Web remains dedicated to supporting third-party research on hemp CBD investigated by some of the country’s top scientists.”

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Fibromyalgia

What is fibromyalgia – and can cannabis help?

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One treatment which is growing significantly in terms of both research and usage is cannabis.

With around one in 20 people in the UK and an estimated three to six per cent of the world’s population diagnosed, fibromyalgia is one of the most common pain conditions in the world. 

Anyone can develop fibromyalgia – it affects around seven times as many women as men but can develop in either gender at any age – though its wide-ranging symptoms can make it a difficult condition to diagnose.

Alongside chronic pain, those affected may suffer with extreme tiredness, muscle stiffness, headaches, irritable bowel syndrome and problems with mental processes such as memory and concentration – all of which can be attributed to a number of other ailments. 

While the exact cause of the condition is unknown, it’s thought to be related to abnormal levels of certain chemicals in the brain and changes in the way the central nervous system processes pain messages carried around the body. In many cases, it can be triggered by a physically or emotionally stressful event such as injury, giving birth or the death of a loved one. 

Unfortunately, there is no known cure for fibromyalgia and no remedy to get rid of pain entirely. Instead, patients search for methods to alleviate symptoms, with many opting for a combination of treatments.

One which is growing significantly in terms of both research and usage is cannabis.

The remedy has long been associated with pain relief and as evidence of its benefits mounts, many fibromyalgia patients are choosing to give products such as gels and capsules a try. 

In 2019, a study of 367 patients found that pain intensity decreased when treated with CBD. This was supported by Chaves, Bittencourt and Pelegrini in 2020, with the team finding that phytocannabinoids can serve as an ‘affordable yet well-tolerated therapy’ for symptom relief and quality of life improvements.  

As usage rises, professionals are coming round to the idea of CBD as a prescribed treatment in fibromyalgia, and in 2018 Carly Barton of Brighton became the UK’s first fibromyalgia patient to receive a prescription for medical cannabis. Prior to that, she, along with thousands of others, had been paying up to £2,500 for three months’ treatment. 

Despite many sufferers being reluctant to exercise for fear of aggravating symptoms, it’s another effective way to alleviate pain. Aerobic, resistance and stretching exercises have all been known to relieve pain and stiffness, increase strength and improve mobility in patients, while relaxation exercises such as yoga and t’ai chi can help with difficulty sleeping. 

Research has repeatedly backed up these claims and shown that regular aerobic exercise can improve pain, function and overall quality of life, with a 2017 study stating that “aerobic and muscle strengthening exercises are the most effective way of reducing pain and improving global wellbeing in people with fibromyalgia and that stretching and aerobic exercises increase health-related quality of life”.

While regular painkillers may provide some benefits to fibromyalgia symptoms, one of the most commonly prescribed medications for the condition is antidepressants. The medication is known to boost the levels of certain chemicals (neurotransmitters) that carry messages to and from the brain, and with low levels of neurotransmitters thought to be a factor in fibromyalgia, it’s believed that this boost may ease the widespread pain associated with the condition. 

Many professionals also believe that talking therapies, such as cognitive behavioural therapy (CBT) and counselling, are an effective way to manage symptoms and improve low mood associated with fibromyalgia.  

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Endometriosis

How you can take part in a worldwide survey on cannabis and endometriosis

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The study will help create a clinical trial for how medical cannabis can help endometriosis

Do you have endometriosis and use cannabis to manage your symptoms? Here’s how you could take part in new research.

Researchers from Western Sydney University and the University of New South Wales are keen to find out more about the potential use of cannabis to manage endometriosis pain.

They are looking for participants from across the world, who have been told by their doctor they have the condition and who consume cannabis – either through a prescription or illegally –  to manage symptoms. 

Results of this survey will help design an upcoming clinical trial to explore the effectiveness of medicinal cannabis for endometriosis.

Endometriosis is the second most common gynecological condition in the UK, affecting around one in 10 UK women – although frequent misdiagnosis and a lack of understanding means this figure may be higher.

Despite its prevalence, according to Endometriosis UK, it takes an average of seven and a half years from onset of symptoms to get a diagnosis.

It happens when tissue similar to the lining of the womb starting to grow in other places, such as the ovaries and fallopian tubes, causing inflammation, pain and the formation of scar tissue. A wide range of debilitating symptoms include pain in the lower abdomen and back, nausea and intense fatigue.

There is currently no cure for the chronic condition and treatment is limited to painkillers, hormonal contraception, or surgery. 

However, there is a growing amount of anecdotal evidence for the efficacy of cannabis in managing some symptoms such as pain and nausea, with some early suggesting cannabinoids can help with stopping the endometrial cells from multiplying, regulate nerve growth and reduce inflammation. 

Researchers in Australia hope to continue to increase the information on cannabis use for endometriosis, and to plan a clinical trial to investigate the safety, tolerability, and effectiveness of a standardised and quality assured medicinal cannabis product for pain and associated symptoms.

This survey is open to patients worldwide who must fulfil the following criteria:

  • Aged between 18-55 years of age
  • Been told by your medical doctor that you have endometriosis 
  • And you must have used cannabis or cannabinoid-based products (eg CBD, cannabis oils, dried bud (flower) with known levels of THC and/or CBD, or non-legal cannabis) in the past three months specifically for the purpose of managing your endometriosis pain or related symptoms.

The survey expires on 31 March 2021, find out more here

Click here to participate

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