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Study: Could CBD help with alopecia?

A new study on topical CBD finds it may be as effective as other treatments on the market but further testing is needed

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Alopecia: A number of hair products on a white background including two hairbrushes, a bottle of oil, a spray bottle and two towels

A new study on alopecia revealed that topical CBD use over time may help with regrowth. It could offer an alternative, non-invasive treatment for the condition.

Androgenetic alopecia can sometimes be referred to as female or male pattern baldness. It can cause thin or bald patches across the head. There are different forms of alopecia such as alopecia areata that can cause hair to fall out in patches, these may connect becoming noticeable. It develops when the immune system attacks the hair follicles. It may also affect eyebrows, eyelashes and face while developing over time.

Alopecia study

The researchers stated that the endocannabinoid system (ECS) may be involved in maintaining cellular homeostasis by regulating inflammatory response and regenerative progress.

The endocannabinoid system has three core components: endocannabinoids, receptors and enzymes. These receptors can be found throughout the body. Endocannabinoids bind to them to send signals that the system needs to be active and do something. The main two receptors are CB1 which is found in the central nervous system and CB2 in the peripheral nervous system. Cannabinoids are thought to bind or influence these receptors.

All of these receptors relate to hair follicle function. Researchers examined if blocking the CB1 receptor on the hair follicle with CBD could have a result in hair shaft elongation. They noted that the effects are dose-dependent and higher doses may have a different effect.

This study was conducted to determine if daily topical application of hemp oil high in CBD concentration would result in significant hair regrowth in the area of the scalp most affected by androgenetic alopecia (AGA)

READ MORE  CBD-enriched cannabis has potential to treat cancer - study

Alopecia treatment

The study took 35 participants with AGA and gave them a once-daily topical dose of CBD. This was on average 3 to 4 mg per day for six months. The researchers conducted a hair count of the greatest areas of alopecia before treatment and after six months. To facilitate this,  a clear acrylic mould with a cut out was made of each person’s head.

When it came to results, the men reported more regrowth than women and the vertex area did better than the temporal ones. vertex transition point refers to the area where the scalp goes from a horizontal to vertical while the temporal areas. There was an increased average of 95 percent in non-vellus hair after six months of daily use. All subjects reported some regrowth with no adverse effects.

The researchers felt that the CBD treatment offered comparable effects to other treatments on the market and could be used alongside them to maximise the effects. However, they stressed this combination would need further testing.

The authors wrote: “Topical CBD formulation has comparable results to finasteride and comparable results to 5% minoxidil once daily foam. Since the CBD works through novel mechanisms different from finasteride and minoxidil, it can be used in conjunction with these current drugs and would be expected to have synergistic effects.”

Read more: CBD Guides: What’s the best way to take CBD?

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Beauty & Skincare

95% of patients with rare skin condition report improvements with cannabis topicals

Epidermolysis Bullosa causes severe blistering which can become infected after any trauma or friction.

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Skin condition: A white cream with a green cannabis leaf on top. It is surrounded by dark oil bottles and a spoon that has cream on it. This is on a dark background

A new study of a rare skin condition has revealed that different preparations of cannabinoids could have benefits for patients with painful Epidermolysis Bullosa (EB).

Epidermolysis Bullosa (EB) is the name of a group of rare inherited skin disorders that can cause the skin to become fragile.

It is thought to be caused by a gene mutation that makes the skin more fragile and any trauma or friction can cause painful blisters on the skin. There is currently no cure but treatment aims to prevent infection and reduce symptoms.

The study from the Netherlands and the United States analysed EB patients on five different continents who reported using cannabis preparations as a treatment for their rare skin condition.

The data is published in the Orphanet Journal of Rare Diseases. The patients reported using topical cannabinoid products in addition to inhaling cannabis flowers. They also consumed cannabis-infused edibles.

Patients were given a survey on their skin condition that focused on monitoring effects including perceived EB symptom changes, medication use, and side effects. 

Skin condition results

Results recorded that 95 percent said the topicals improved their overall skin condition symptoms with 94 percent stating their pain levels were decreased.

A further 91 percent said they had less itching and 81 reported wound healing was improved. Most of the participants at 79 percent said they had decreased their medication for their skin condition. The only side effect with a notable significance was dry mouth at 44 percent.

The authors noted that cannabis improved patient’s “perception of pain, pruritus, wound-healing, and well-being … and reduced concomitant medication use.”

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They wrote that: “Future prospective controlled clinical studies are warranted to elucidate the potential role of CBMs (cannabis-based medicines) in EB treatment.”

Read more: Parkinson’s disease and CBD: New study reveals potentially positive effects

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New Gen-Z CBD beauty brand launches with 1.7 million views on TikTok

The new brand, Love MeMeMe aim to encourage people to take time out for self-care.

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Gen-Z: A group of young people hug in front of a camera while all are wearing a light pink colour.

A new CBD brand, Love MeMeMe has hit 1.7 million views on TikTok by sharing their hashtag, #metheloveofmyownlife.

The brand offers a range of gender-neutral, self-care CBD beauty items including lip balms, hair masks and body butter. The brand is aimed at Gen-Z consumers rather than millennials or baby boomers.

As part of a marketing campaign, Love MeMeMe partnered with TikTok influencers to launch the products. Liana Jade, Miah Carter, Max Ragan, Chloe Rose, Bobbie, Elvira Styles and Hani Hans endorsed the brand on the platform. Each one of the influencers explained what self-love means to them and what their self-love tips are.

The range combines not just CBD but active ingredients such as retinol and Vitamin A and E. The bright colourful packaging is not only eye-catching but the price point is easily accessible with products starting at £8. There are nine products in the collection which launched this week.

Gen-Z marketing

Gen-Z consumers who are described as those born between 1997 and 2012. This explains the TikTok focus, it is estimated that by the end of this year, there will be more Gen-Z users on TikTok than on Instagram with 37.3 million Gen Z users. Although Snapchat is one of the biggest platforms amongst this age group, it is thought that the brand will overtake it by 2023.

It’s working for Love MeMeMe who have gained 1.7 million views on the platform in just under a week.

Gen-Z: A group shot of cosmetics together. The packaging is pink and red with a purple logo

Gen-Z CBD use

These aren’t unusual figures for Gen-Z who are described as the first wave of truly digital native consumers. They aren’t just used to consistent connectivity but also, CBD and cannabis consumption is becoming normalised.

READ MORE  Government study of CBD labs gives vote of confidence to industry

In the US, a recent study from a Seattle-based cannabis data brand, Headset revealed that Gen-Z is the fastest-growing segment of the cannabis industry. In the past year, sales to Gen-Z surged by 127 percent with the biggest percentage among females. This is an even bigger amount when compared to sale increases among other generations. Millennial sales increased by 46 percent, Gen X increased by 29 percent and baby boomers by 5 percent.

Headset noted: “This demographic will continue to drive exponential growth, so it’s important to pay attention and understand their preferences.”

The same study also showed that Gen-Z prefers to smoke cannabis with only 10 percent spending money on other ways to consume CBD. This is down from 15 percent for other generations. They are also less brand loyal as well with only 20.6 percent preferring to stick to one brand.

Read more: CBD beauty sales soar: What does it actually do?

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Jay-Z launches new CBD and THC infused wellness collection

The collection marks The Parent Company’s first collection of wellness products starting with topicals and oils.

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Jay-Z: A photo of the rapper Jay-Z against a black background. He is holding a microphone and rapping into it

Jay-Z’s cannabis brand The Parent Company has launched its first line of lotions and tinctures in three categories – well balanced, well relieved and well-rested.

The Parent Company is a vertically integrated cannabis company based in California. This is their first collection of wellness products that contain CBD and THC under the Caliva label, ‘Well by Caliva’.

The three products allow customers to choose which product best suits their needs. It was created based on recent data showing the top reasons that people turn to cannabis: relaxation, improving sleep quality and pain management.

Jay-Z: A line of three bottles of oil in orange, yellow and blue from jay z's new collection on a white background

Image credit: The Parent Company

The lotions come in two forms: a muscle and joint lotion and a head, neck and shoulder lotion. The Well Relieved muscle & joint lotion offers a blend of CBD: THC mixed with clove and frankincense essential oils for a warm, spicy aroma. Their head, neck and shoulder lotion contains over 3oo mg of cannabinoids with calming lavender essential oil.

The launch announcement comes just days after Jay-Z’s wife, Beyonce announced she had turned to CBD for relief following a gruelling tour schedule.

Parent Company COO Dennis O’ Malley said: “We are excited to be expanding our wellness category with the release of our line of CBD and THC lotions and tinctures. As part of The Parent Company’s mission to provide access and entry points into cannabis, we knew that a wellness line that uses the combination of CBD and THC for more powerful effects would be attractive to consumers. Our new line of Well by Caliva products offer the same high quality that consumers have come to trust from The Parent Company, at an affordable price.”

Jay-Z - two bottle of topical CBD THC lotion in red and pink with their boxes beside them on a white background

Image credit: The Parent Company

The Parent Company was formed in 2021 which holds a product portfolio of eight cannabis brands such as Monogram by Jay Z. Jay Z serves as the chief visionary officer for the company. He established their social equity ventures initiative which was created to break down the systematic barriers Black and other minority entrepreneurs face as they attempt to participate and lead in the legal cannabis industry.

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Read more: Ziggy Marley releases new wellness line for pets

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