Successful insomnia trials using cannabis

Zelira Therapeutics Ltd, said its trial focused on its ZLT-101 cannabis product, which was given to 23 patients over 14 nights.

Results showed that patients, who received either a 0.5ml or 1ml dose each night, saw “statistically significant and dose responsive improvements” in Insomnia Severity Index (ISI) scores.

Australian firm Zelira, which has currently released two products under the HOPE brand in multiple US states and hopes to launch globally this year, said patients experienced an average ISI score decrease of 26 per cent.

In addition, said the company, the trial also demonstrated that the effects of ZLT-101 may also be dose-dependent. Patients who received a higher dose demonstrated a higher average ISI score decrease of 36 per cent. 

Insomnia is a sleep disorder which causes people to have trouble getting to sleep or staying asleep, and which up to a third of people in the UK could suffer from, according to the UK Mental Health Foundation.

The condition can also cause prolonged tiredness throughout the day, feeling irritable and unable to concentrate.

Dr. Richard Hopkins, managing director, ex-US markets, at Zelira Therapeutics, said: “We are delighted as these results have exceeded our expectations. Globally we are the first company to take a full-spectrum cannabis product and test it for efficacy in the insomnia space.”

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