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The ‘mother of all cannabinoids’ – what is CBG?

New studies show the potential benefits of this lesser-known cannabinoid

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THC: A collection of CBD bottles and cannabis leaves on a white background

There are hundreds of cannabinoids in cannabis from CBD to THC. Although CBD feels like its popping up in everything lately, the industry is looking for the next big thing – cannabigerol (CBG).

What is CBG?

Cannabigerol is one of the cannabinoids found in cannabis. It is sometimes referred to as ‘the mother of all cannabinoids’ because it is the precursor to CBD. Other cannabinoids are derived from cannabigerolic acid (CBGA), an acidic form of CBG.

There is very little CBG in plants often as low as one per cent so it makes CBG more expensive than CBD products. CBD is much more available in plants at 20 to 25 per cent. CBG tends to be made from younger plants which contain a higher percentage. THC and CBD both begin life as CBGA before maturing and THC goes on to become CBN in older plants.

It is thought to work the same as CBD in that it interacts with our endocannabinoid system via receptors that are found all over the body. In particular, it may bind to the CB1 receptors in our nervous system or CB2 receptors in our immune system.

It is thought to potentially strengthen the function of anandamide which is a neurotransmitter that affects our pleasure and motivation. It also regulates appetite, sleep and pain relief.

What is CBG good for?

There have been a few studies that show the potential benefits of CBG.

A study from 2020 revealed that CBG may help to fight against antibiotic resistance.

Researchers identified CBG as an antibacterial compound that may serve as a lead for new drug development. Their study found that it was not only antibacterial but it was effective in mice fighting a resilient form of bacteria referred to as methicillin-resistant Staphylococcus aureus (MRSA).

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A more recent study from 2021 revealed that it may help in the fight against obesity.

The researchers synthesised three different CBG derivatives, HUM 223, HUM 233, HUM 234. In tests on mice, they discovered that HUM-234 may offer potential as an obesity treatment drug.

The mice were divided into groups for the study; one given just a high-fat diet (HFD), another given an HFD and CBG then one given an HFD and HUM-234. The researchers discovered that in comparison to the other groups, the mice on HUM-234 gained weight much slower and their livers were in a better condition with less fat build-up.

The researchers wrote: “The high-fat diet mice showed liver steatosis while the HUM 234 treated mice livers revealed almost no steatosis. The livers of the mice on CBG showed almost the same levels of steatosis as those on the high-fat diet.”

Should I take CBD or CBG?

Why not combine both? CBD and CBG can actually combine to offer potentially better benefits together. This is often referred to as the entourage effect. Each cannabinoid has unique effects and benefits, and their behaviour may when combined with other compounds.

That said, if you do prefer the idea of one or the other then these are some of the benefits of CBG

CBG for appetite stimulation

A study from 2017 revealed that a form of CBG with no THC was an effective appetite stimulant in rats. It is thought that it may be able to help with cachexia, the muscle-wasting and severe weight loss associated with cancer.

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CBG for glaucoma

In one study, researchers treating cats with glaucoma used drops with CBG and Δ9-tetrahydrocannabinol.  They noticed there was a reduction in eye pressure but an increase in aqueous humor outflow which is a liquid that provides nutrition to the eyes.

CBG for Huntingdon Disease

In another study from 2015, researchers discovered that CBG may have neuroprotective properties when it comes to Huntington disease. They examined mice with an experimental model of Huntington Disease. They noted that CBG may act as a neuroprotectant minding nerve cells from damage while improving motor defects. It also helped to preserve striatal neurons against 3-nitropropionic acid toxicity.

CBD for Inflammatory Bowel Disease

A study from 2013 on mice that had inflammation similar to IBD induced in their colons revealed that it may help to reduce the production of nitric oxide. It also reduced the inflammation present.

How do I know if CBG works for me?

The best way to start taking it is to find a product that suits your needs. If it’s a muscle problem then maybe topicals may be better suited as the product can target the exact area. If you aren’t a fan of the hemp after-taste then maybe edibles may suit you?

As with CBD, it can take a while to notice the effects of CBG so keeping a note of the effects you do notice is a great way to monitor your intake and the benefits.

It is worth doing your research to find a reputable brand that you can trust. As it is difficult to produce and present in plants at a lower percentage, it may be more expensive to buy. The most common CBG product on the market is oil but there are increasingly other options available including CBG vaping e-liquids.

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Is CBG legal?

It is legal, as long as the production does not exceed the legal allowance of THC. THC is still a controlled substance in the UK.

Can CBG get me high?

Nope!

CBG is non-psychoactive which means they will not get you high like THC can. The same can be said for CBD.

Read more: CBD isolate may reduce the symptoms of Parkinson’s Disease

Wellness

Find your balance with premium, vegan and cruelty-free CBD patches

Una Patches is an innovative CBD patch brand. Here, its founder reveals what makes it unique.

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Una Patches: Cbd patches
With patches, CBD is absorbed through the skin, releasing CBD over a 24-hour period.

Una Patches is an innovative CBD patch brand offering premium patches that are blissfully simple to use and truly sustainable. Here, its founder reveals what makes it unique.

Una Patches focus on doing CBD differently. With patches, CBD is absorbed through the skin, releasing CBD over a 24-hour period, which avoids any fluctuations that may arise from other delivery methods. 

The patches boast an impressive rap sheet; they are biodegradable, waterproof, vegan & cruelty-free. Plus, Una Patches are small, discreet and comfortable to wear- you won’t even realise you have one on.Una Patches: CBD patches

Una Patches is a WOC-owned business, founded by Annu, a medicinal chemist by training.

Annu speaks openly about her background and experience within business.

“I’m proud to be a WOC-owned business. I’m from a family of entrepreneurs so it feels very natural and fulfilling to step into this space,” she said.

The wellness and CBD space can be very whitewashed and often adopts eastern teachings for the benefit of others. I hope that Una Patches can continue to bring representation to this space and begin to educate and expand people’s knowledge.”

Annu wanted to launch CBD products with a difference. As a result, she delved into the science and conducted extensive market research. In doing so, she learnt all about the benefits of transdermal patch delivery versus other delivery methods which usually waste large amounts of CBD. 

This meant there was a quicker, easier and more convenient way for people to get more from their CBD. Plus, they have the credentials to back it up – with 3rd party lab tests and medical device rated patches to ensure quality and purity.

As well as their commitment to quality, sustainability is a core belief for Una Patches. Not only does their unique delivery method mean they have a zero-waste product, but they are also the first climate positive CBD brand.

Una Patches: CBd patches

The patches are completely biodegradable, and their packaging is fully recyclable. Their supply chain has also been designed to minimise carbon emissions by choosing local manufacturers wherever possible. 

Climate positivity means the brand doesn’t just offset their unavoidable carbon emissions, but they go above and beyond to contribute towards projects that positively impact people and the planet. 

This year, Una Patches chose to contribute towards the Kasigau Corridor project. The project, based in south-east Kenya, protects over 500,000 acres of forest. Whilst safeguarding the forest and wildlife, the project has also led to the creation of over 300 jobs, 15 new schools, safe drinking water and the formation of hundreds of women’s groups.  

Whilst only being launched in April 2021, Una Patches are already making waves within the industry, having won the ‘Best CBD Brand’ at the Marie Claire Sustainability Awards.

Una Patches: CBD patches

Annu speaks on the successes of this year: “I’m excited and proud when I reflect on this year. For Una Patches to enter the market as a new brand and win the Marie Claire Sustainability award is so rewarding and still a big pinch me moment for us! I know we can continue to make waves as a small independent brand. 

“Getting customer feedback is my favourite part of it all. It makes everything worth it and I hope to keep raising our voice to reach more people.”

So, whether you’re looking to ease away daily stresses, relax for a peaceful nights sleep or calm your aching muscles – Una Patches may be your new best friend.

A pack of 30 patches retails for just £29.99, they make for the perfect gift… or as a little treat for yourself! 

You can find out more about the brand here: unapatches.com

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CBD guides: How do these unusual CBD products actually work?

We’ve rounded up some of the more unusual products out there to see how and if the science stacks up

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CBD: An illusrated collection of CBD products including oils, balms and capsules

Some of the more unusual CBD products make us wonder, how does that work? We examine the science and just how effective they actually are.

There is so much more to CBD than just oils, edibles or capsules. While the marketplace can seem completely overwhelming, some methods of taking a dose can be a bit more difficult than others. We examine some of the more unusual options out there from shampoo to sports bras to see if they could really work.

CBD toothpicks: A bunch of toothpicks

CBD toothpicks

Some people, especially athletes, chew on toothpicks for different reasons such as oral hygiene, habit or quitting smoking. What if your pick could actually help you to stay calm, especially in the middle of a game?

The idea behind these toothpicks is that as you chew or suck the pick, it releases CBD into the mouth. The CBD then enters the bloodstream through the tissues in the mouth.

Some brands will add other herbs to the toothpicks including spilanthes which induces saliva. The more saliva you produce, the quicker the CBD will get to work. The toothpicks can also be flavoured too meaning there may be no strong hemp aftertaste in the mouth. Perfect for those who aren’t a fan of the flavour.

There are some suggestions that CBD toothpicks may help with preventing gum disease. This could be because CBD is thought to be antibacterial helping to destroy bad bacteria in the mouth. It could also be because toothpicks in general are used to remove bits of food stuck between the teeth that can cause cavities. It may help those experiencing dry mouth as a side effect of medication as it helps to produce more saliva.

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It’s ideal to use the pick for between 20 to 50 minutes before discarding it.

CBD: A man sleeping on a comfortable pillow with a clock in front of him on the night stand

CBD pillows

CBD pillows hit the headlines in 2020 after discount store B&M released their own version for UK£10. Sadly, the original CBD pillows appear to be a bit higher in price starting at US$100 per pillow.

But how do they work?

CBD pillows work using a technology called ‘microencapsulation’. They are filled with millions of tiny little capsules containing CBD which burst under your head as you roll over in your sleep. It is thought that the CBD is then absorbed through your skin and hair follicles.

There are some positives to the CBD pillow in that it could be a great option for those who are struggling with poor quality sleep. It allows the user to keep a steady dose of CBD going throughout the night in comparison to edibles or oils which may wear off after a while.

But there are also negatives to consider too. It is impossible to know how much CBD you are absorbing. It is worth noting that your pillowcase will need to be washed which means the CBD will fade over time meaning you may need to invest again or buy a top-up spray or pillowcase cover.

CBD: A woman holding her knee after running

Athleticwear

CBD sportswear works with the same technology as the pillowcases. The knitted fibres contain millions of microcapsules of CBD which break as you move applying it to the skin where it is absorbed.

It has much the same problems as the pillowcases too in that it is impossible to know how much we absorb this way if any at all. Also, the clothing will need to be washed far more frequently than the pillowcases meaning the CBD may wear off faster.

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The idea behind the CBD infused sports bras and leggings, is that it works as a preventative method stopping muscle pains before they happen.

CBD: A wooden toothbrush with a sprig of mint and a small bottle of CBD

Toothpaste

Out of all the items listed here, CBD or hemp toothpaste may actually be the one with the most promise.

It is difficult to find CBD toothpaste in the UK although this may change soon. Colgate recently moved into the hemp toothpaste market by purchasing the American brand Hello. They have since filed three patents for CBD toothpaste formulas.

A study from Queensland University and Botanix Pharmaceuticals revealed that CBD may have strong antibacterial properties. The study examined CBD’s ability to penetrate and kill bacteria such as Neisseria gonorrhoea, yes gonorrhoea. It can do this because of its ability to break down biofilms to kill bacteria within. Plaque that gathers on our teeth is also a biofilm.

Also, toothpaste and mouthwashes that contain just hemp extract have a lot to offer. It is thought to naturally whiten teeth, prevents decay, and prevent gum disease. The anti-inflammatory properties may be the reason why it could help to prevent gum disease. It could also help to reduce the swelling, redness and pain of gum disease or gingivitis.

CBD shampoo: A collection of bottles containing CBD against a yellow background.

CBD shampoo

Shampoo or conditioner containing CBD may have some benefits when it comes to hair loss. While some hair loss happens naturally every day, there are some people who lose greater amounts than others. There are many reasons as to why this may happen including increased stress, hormonal changes, traumatic events or even genetics. There are also conditions such as alopecia where the hair falls out naturally.

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A study from 2021 revealed that people who applied it to their hair and scalp for six months saw successful regrowth. The results were more promising in men than women.

It’s also worth noting that CBD may have an effect on sleep quality and anxiety which contribute to stress. If hair loss is caused by these factors then it could have an effect. Although it’s impossible to know how much CBD we absorb through our scalp or hair when we wash it with these shampoos.

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Excite CBD on the benefits of a daily dose of gummies

The team at Excite CBD explain why their tasty gummies are perfect for a daily dose.

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Excite CBD: A tub of colourful gummies

The team at Excite CBD explain why their tasty gummies are perfect for a daily dose – and why CBD remains controversial despite its benefits.

Excite CBD has been created to provide customers with a wide range of high-quality products at affordable prices.

All our products are lab tested for purity and potency, so guarantee customer satisfaction every time.

CBD is a natural substance extracted from the cannabis plant, it has been used for thousands of years to treat a wide range of health problems.

CBD is the latest trend in health and wellness. It’s a natural substance that has been shown to help with anxiety, chronic pain, depression, insomnia and more.

In recent years, however, CBD has become increasingly popular as an alternative treatment for anxiety and depression. The use of CBD oil in treating these conditions remains controversial, but there’s no denying that many people swear by its effects.

Many people are familiar with THC (tetrahydrocannabinol), one of over 100 cannabinoids found in cannabis that gets you high when you smoke marijuana or use it in edibles. But not everyone knows about CBD (cannabidiol). Unlike THC, which can make users feel stoned or euphoric (depending on the amount consumed), CBD doesn’t have any psychoactive effects. In fact, many people report feeling relaxed after taking it for a few days – but there’s no getting high involved at all.

So why isn’t everyone talking about this?

One reason could be that most products containing CBD aren’t legal everywhere yet. Another reason might be fear of what your friends will think if they see you using something like an oil or gummy bear infused with CBD. However, CBD is fully legal in The UK since January 2017.

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Excite CBD strength

Most brands offer one or two strengths of CBD oil which can be difficult to choose between when you’re not familiar with the product. Excite offers three different levels (500mg/1000mg/2000mg) so users can find their perfect strength without having to commit to one particular flavour or brand.

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We understand not many people enjoy taking CBD via the oil option, so we offer our hugely popular fruit flavoured gummy sweets with added CBD. Each gummy contains 25mg of CBD and is probably the easiest and most delicious way to get your dosage of CBD.

Excite CBD gummy

It’s no secret that CBD oil is a great alternative to pharmaceutical medications. But the truth is, taking pills and oils can be messy and inconvenient.

The good news is there’s an easier way! Excite CBD gummies are made with all-natural ingredients like organic fruit juice, raw honey powder, and pure CBD extract. These delicious little candies come in five flavours – orange, lemon & lime, strawberry & kiwi, blue raspberry and watermelon – so you get your daily dose of cannabinoids without any fuss or muss.

Our gummies contain 25mg of zero spectrum hemp extract per piece (that’s about one serving), so they’re perfect for everyday use as a maintenance supplement or for when you need some extra relief from pain or anxiety. Plus they taste great!

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