A two-year research review has shown CBD to have a significant positive impact on anxiety and stress.
There are many pressing questions about CBD. How effective is it? How much should I take? What conditions will it help?
A new study — the first meta-analysis by a nutritional supplements company on cannabinoids— aims to shed some light on those questions.
The report was produced by Florida-based Nutrition Formulators and published in the peer-reviewed Innovare Journal of Medical Science.
Examining worldwide clinical papers from 2019 and 2020, this is what researchers found:
Anxiety & Stress
In a review of 76 articles spanning the past two years, more than 70 percent of cannabidiol (CBD) research on anxiety and stress showed positive outcomes.
The meta-analysis focused on CBD isolate and grouped the research into several categories, including CBD impacts on depression, sleep, panic attacks, dementia, inflammation, metabolism, behavior, Parkinson’s disease, and psychiatric illnesses. Human and animal studies were both included in the review.
Dr. Marcelo Ferro, lead author and biochemist with Nutrition Formulators said: “After spending 10 months reviewing the research, I was surprised at how many people with anxiety and depression could be helped by incorporating CBD into their lives, but I was also aware how important it is to do more research, especially on the impact of CBD on liver function.”
When looking at anxiety, the studies show that CBD reduces anticipator anxiety, such as speaking in public by affecting the part of the brain that processes emotional information.
The analysis also showed a 66.6 percent positive improvement for clinicians using CBD as an alternative treatment for depression.
One of the larger questions which the study explored, was how much CBD should be used.
The dosing in the reports varied widely from 50mg to 600mg daily dosing. Much more research is needed on CBD’s side-effect impact on liver function as well as the how CBD interacts in the body. In addition, the study’s authors cited the need for larger population trials that would achieve a statistically significant measure.
“This is just a stepping-stone to understanding more about the amazing CBD compound, how it may be helpful to so many, but also what additional information we need to know so that people can use it as safely as possible,” said Adolfo Graubard, Nutrition Formulators, CEO.
“So many of our CBD business clients are looking for research-based information to educate their customers, this report is a step in that direction.”
NFI is currently working on additional CBD studies focusing on neuroinflammation and autism in partnership with several research institutions.
Clinical trial will assess if CBD can be used to treat PTSD
A new clinical trial could be a breakthrough moment for the treatment of PTSD
US biotech firm Ananda Scientific has launched clinical trials of a cannabis-based treatment for post-traumatic stress disorder (PTSD).
The company has teamed up with New York University Grossman School of Medicine to carry out the eight-week study.
The Phase II double-blind, randomised trial will involve 120 patients in a large scale placebo-controlled experiment which could be a breakthrough moment for the drug.
If successful, the trial will be an important step on the journey to winning regulatory approval Ananda’s Nantheia treatment, a drug incorporating CBD into a liquid application.
PTSD is a common mental health disorder which occurs in people following a traumatic experience and is a particular problem among people who have served in the armed forces.
A 2014 study found as many as 12.9 percent of US soldiers who served in Iraq displayed some symptoms of PTSD.
Recent months have seen warnings health workers on the front line during the Covid-19 crisis could also be experiencing PTSD.
A study in the British Medical Journal compiled earlier this year found 39.5 percent of staff on critical care wards ‘met the threshold for probable clinical significance’ when surveyed for PTSD symptoms.
The study will also evaluate its impact on patients with neurocognitive impairments resulting from a traumatic brain injury.
Sohail R. Zaidi, Ananda’s president, said: “This is an important milestone for Ananda’s clinical development program, and we look forward to continuing to work with the NYU Grossman School of Medicine.
“We are impressed by the scientific rigour and professionalism of the NYU team in getting a cutting-edge program in place to test the efficacy of our very promising drug.
“The initiation of patient enrolment in this study reinforces our commitment to our goal of improving health and wellness empowered by cannabinoid science.
“This is also an important step in our efforts to provide patients with PTSD with potentially improved therapeutic options.”
This trial is being led by Esther Blessing, assistant professor of psychiatry and Charles R. Marmar, chair of psychiatry.
Dr Marmar leads NYU’s PTSD research programme and is a leading expert in clinical trials for innovative treatments for PTSD and related conditions.
He said: “We are excited to get this important trial underway. Our collaboration with Ananda Scientific allows us to progress in the development of evidence-based CBD products for this debilitating condition.”
Why are people using CBD?
New survey data reveals why people in the US are consuming CBD – here are some of the key findings.
New survey data reveals how and why people in the US are consuming CBD – here are some of the key findings.
Data intelligence firm New Frontier has released two new reports providing in-depth analysis on CBD consumer groups in the US and the factors shaping their behaviours.
For the survey, respondents were grouped into four cohorts based on their primary reason to consume CBD including; medical, pain management, unwinding and general wellness.
Just over half of those described as ‘unwinding’ consumers are under the age of 35, while most who use it to manage pain are aged 55 or older, according to the findings.
Medical and general wellness consumers are roughly evenly distributed across age groups.
A whopping 92 percent of medical users reported having a ‘positive impression’ of CBD and 71 percent have recommended it to someone they know.
Unsurprisingly, medical users were more likely to consume CBD on a daily basis and spent more on the supplement, with one in four claiming to be spending more than $100 per month on CBD products.
The majority of those surveyed said they used CBD for pain management and were “highly satisfied” with CBD and most likely to believe that it has “valid medical uses”.
But in general this group was “uninformed” about the cannabis market, says the report, and only one in five weren’t interested in learning more.
This group was younger than the average and nearly three-quarters said they had discussed CBD with friends, while more than 90 percent have friends or family who also use it.
By contrast, general wellness consumers were among the least likely to have had a conversation about CBD (11 percent) and nearly 1 in 5 (17 percent) did not know any friends or family who consume it.
Oils and tinctures were the most popular consumption method, followed by topicals, edibles and drinks and vaping, with CBD in capsule and pill form the least common.
Concluding key takeaways from the survey, the authors write: “The deepening fragmentation of the CBD consumer market will continue as consumers become more familiar with the products, and more targeted in the ways by which they integrate CBD into their lives.
“While medical consumers are most likely to be regimented in their use, more likely to be brand-loyal, and most focused on dosing, other consumers groups are far less entrenched in their product preferences or consumption habits.”
While 30 percent of surveyed consumers expected their CBD usage to increase in the next six months, just under half (49 percent) said they did not have a preferred brand.
New Frontier Data founder and executive chair, Giadha A DeCarcer, noted: “As the market is flooded with more product choices, CBD brands and retailers would be well-served to delineate and target their consumers as they would in any other mainstream product category.”
See the full report at New Frontier Data
Friends and CBD founders donate profits to mental health charity
10 percent of the brand’s profits will go to the Mental Health Foundation this month
Two friends who co-founded a CBD brand after experiencing anxiety, are donating a percentage of the company’s profits to a mental health charity this month.
Best friends and CBD co-founders, Laura Walton and Catherine Meardon know the importance of looking after your mental health.
Both of them have experienced anxiety either personally, or through a loved one.
This June, the pair who co-founded CBD brand Moi+Me, are donating 10 percent of their profits to the Mental Health Foundation to help raise awareness.
The charity provides support for those experiencing mental health issues, as well as campaigning to raise awareness and reduce stigma.
The friends and former colleagues founded Moi+Me after Laura’s struggles with anxiety after losing her mum.
She says discovering CBD, along with other tools and being able to be open about her experience helped her find her “way out”.
As a friend, Catherine has found it difficult to know what to say and together they wanted to build a brand that could provide tools and support, as well as taking the confusion out of CBD.
“Both of us have been touched personally by anxiety, either through our own suffering or that of those we love,” said Laura.
“I used CBD along with other tools during her mental health journey and found them to be a great support, but I didn’t want to only create a brand or product, we want to help support as much as we can by encouraging people to take extra care of themselves and have self-love.”
She added: “It is our mission to raise further awareness of mental health, we are fully aware it can still be hard to be open about mental health in fear of being judged so by supporting this charity who in turn helps others also suffering feels a perfect fit for our brand.”
The concept for Moi + Me came from the idea that our busy lifestyles leave us feeling pulled in different directions with little time for reflection and self-care.
The range includes CBD balm, temple roller, peppermint oil mist and massage candle to encourage customers to take time for themselves.
Catherine added: “We both understand the importance of getting your life balance right. If you don’t allow time in your life for reflection and relaxation, things can very quickly feel on top of you.
“Our busy lifestyles can leave us feeling like you have one soul and two minds. One ‘Moi’ side of us is thriving externally while the other ‘Me’ side feels tired, worn out and has too much on.
“We’ve designed our high-quality, pure CBD product range to help bring moments of calm into your daily routine through a combination of stimulating flavours and scents.”
Access mental health information and support via the Mental Health Foundation
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